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Fas相關(guān)死亡結(jié)構(gòu)域蛋白重組兔單抗

簡(jiǎn)要描述:Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination an

  • 產(chǎn)品型號(hào):bsm-61231R
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時(shí)間:2025-03-03
  • 訪  問(wèn)  量: 81

詳細(xì)介紹

Human
WB,IHC-P,IHC-F,ICC/IF,IF,Flow-Cyt
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

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